Bio3 Research intends to identify, develop and bring to commercial fruition new or highly innovative therapeutical agents in diseases related to HMGB1 protein over-expression and HMGB1 biological properties.

Strong over-expression of HMGB1 it has been detected in:

Restenosis;
Atherosclerosis - induced by angioplasty;
Atherosclerotic plaque;

HMGB1 proliferation activity is also tested in:

Connective tissues repair.